Oct 20, 2025
3 min read
Superracugia usually denies seriousness maintaining memories and good mental health in the 80s.Saint Samtu knew that each of these people resists the processes of the brain or their conjectures.They are all mental abilities and their good life can help prevent diagnosis.The findings may inspire new ways to delay or prevent dementia.
These 80-year-olds have the memory of 50-year-olds.Scientists finally know why
SuperAger's 25-year study shows that cognitive decline is not an inevitable part of aging.
- 19 October, 2025
- Northwestern University
- The smile determines the daily routine by keeping the brain memory of healthy people and the brain well in the 80s.Scientists from North America have discovered that these people who oppose brain bread are either harmful or harmless.Their brains are young people developing, and their social lives can help protect understanding.Understanding can hold new ways to delay or prevent its path.
- Superagers are people over the age of 80 who have the same memory as someone under 30, showing that exceptional cognitive health can last a lifetime.
- They tend to be highly social, maintain strong relationships and lead active lifestyles, and their brains appear to be resistant to the buildup of plaques and tangles associated with Alzheimer's that often lead to memory loss.
- Ongoing research is revealing powerful insights that could help scientists develop new approaches to or even prevent the delays associated with neurodegenerative diseases such as Alzheimer's disease and frontotemporal diseases.
For the past 25 years, researchers in northern medicine have tested people 80 and older, known as "superagers," to find out about scenia.
These are the beautiful things that make memories of people for the 30 years old men, requiring the most important idea of the cycle.
During many years of research, scientists have observed that SuperAgers often share lifestyle and personality traits, such as being more social and outgoing. However, according to Dr. Sandra Weintraub, a professor of psychiatry, behavioral sciences, and neuroscience at Northwestern University Feinberg School of Medicine, the most surprising findings came from looking directly into their brains."What we found in their brains was devastating to us," she said.
By breaking down the moral and ethical implications of killing, scientists are developing new ways to increase the risk and at least prevent Alzheimer's disease and other forms of dementia.
Corresponding authors of the new journal found that "our findings show that special memory is not only possible, but is associated with a neural form that aims to keep life alive."
The article was published as a perspective article in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, published in a special issue marking both the 40th anniversary of the National Institute on Aging's Alzheimer's Disease Centers program and the 25th anniversary of the National Alzheimer's Coordinating Center.
The mind of a superwager is tenacity, tenacity
In the late 1990s, the founder of the Northwestert Mesulam Center for the Understanding of the Nervous System and Dementia was MMS, the term "Super Ager" was first coined by Marcel Mesulam.
Since 2000, 290 superagers have participated, and researchers have collected 77 brains from 77 donated superagers posthumously.Some of these brains have been shown to accumulate amyloid and Tau proteins (also known as tangles and tangles), which are hallmarks of Alzheimer's disease, while others have been shown to accumulate altogether.
"What we realized is that there are two mechanisms that lead someone to be a SuperAger," Weintraub said."The first is resistance. It doesn't form plaques and tangles. The second is flexibility. It does, but it doesn't do anything to the brain."
Other important findings:
- Exceptional memory performance: Supagers scored at least 9 points on the delayed word recall test, on par with people in their 50s and 60s.
– Young brain structure: Unlike the typical aging brain, SuperAgers do not show significant thinning of the cerebral cortex – the outer layer of the brain – and even have a thicker anterior cingulate cortex than young adults.This important area of the brain plays a key role in integrating information related to decision-making, emotions and motivation.
- Unique cellular characteristics: SuperAgers have more von economo neurons, which are specialized cells associated with social behavior, and larger entorhinal neurons, which are critical for memory, than their typically aging peers.
- SOCIALIZATION as a common trait: although they have their own lives and different ways of exercising, the community tends to be very social and show strong interpersonal relationships.
“Brain donation could offer scientific immortality”
At the Mesulam Center, SuperAgers are evaluated annually and can choose to donate their brains for postmortem evaluation by Northwestern scientists.
“Many of the findings presented in this article come from studies of brain samples from generous and dedicated SuperAgers who have been followed for decades,” said Dr. Tamar Gefen, professor of psychiatry and behavioral sciences at Feinberg, director of the Feinberg Translational Neuropsychology Laboratory and neuropsychologist at the Mesulam Center.perhaps, offering a kind of scientific immortality.”
The title of the visualization is, "Northwestern's first 25 years." Northwestern authors include Dr. Mesulam and Chiftiz Geula of Counter Cell and Neuroscience at Feinberg and members of the Mesulam Center.
Materials available at Northwestern University.... Note: Materials may be edited for style and length.
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